In 1991, I finally finished the long arduous path to becoming a plastic surgeon. Two years later, after passing my boards, I sighed with relief and looked forward to a long “typical” surgical career. But two events occurred almost immediately that radically changed my vocation plans to anything but ordinary. First, I received a letter from an insurance company denying my request to perform reconstructive breast surgery on my then 33-year-old patient. Their justification: The surgery would be performed on what they considered “an organ with no function.” That letter sparked a five-year legislative campaign to pass laws requiring insurance companies to pay for breast reconstructive surgery following mastectomy. The campaign ended successfully with the passage of laws in thirty-five states, and after several meetings with President Clinton and First Lady Hilary Clinton, many members of Congress, extremely intense work, and the help of thousands—a federal law on October 21, 1998.
The second event occurred just after Thanksgiving in 1993, when my own mother was diagnosed with breast cancer and died from it 9 months later. At that moment, all of my attention turned to stopping the breast cancer epidemic. I knew there had to be ways that women could dramatically lower their risk of this horrendous deadly disease and stop it before it ever started. After searching for clues in the medical literature, I was surprised and delighted to find thousands of studies pointing out exactly why we have a breast cancer epidemic and what we can do to stop it.
The vast majority of these studies were not in obscure journals. Rather, they are well-designed and published in reputable peer-review journals, such as the New England Journal of Medicine. Not surprisingly, they revealed that the American diet and lifestyle are a recipe for breast cancer, and with some simple adjustments, the risk of breast cancer can be made almost negligible.
Cultural Clues
The first clue that our culture is the culprit came from epidemiological studies. Women in Asia, particularly in rural areas, have a much lower incidence of breast cancer1. But if an Asian woman moves to the United States and adopts our diet and lifestyle, within one generation her risk will match that of an American woman. A close inspection of the standard Asian diet verses what we normally eat explains a lot. We consume large amounts of red meat and saturated animal fats enhanced with growth hormones and estrogen-mimicking chemicals, sugar and refined carbohydrates, and alcohol—all cancer-promoting.2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17Asians consume lots of fresh vegetables cooked with spices such as turmeric and garlic, whole soy foods, green tea, mushrooms, and seaweed—all cancer-protecting.18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,3.
Deadly Foods and Habits
Red Meat and Saturated Animal Fats
Let’s take a closer look at some of the common foods in our diet and how they promote cancer. Research shows that frequent consumption of red meat—particularly well-done and grilled—significantly increases the risk of breast cancer. High-heat cooking processes add to the risk because it causes the formation of new carcinogen called heterocyclic amines. Women who regularly eat red meat have a 220%-770% higher incidence of breast cancer.2,3 Meat protein isn’t the only factor in red meat that contributes to its health dangers. Environmental toxins store and concentrate in saturated animal fats found in red meat and especially whole-fat dairy.5,6,7 Many of these chemicals mimic the estrogen molecule or act as growth factors for breast cancer in other ways. Another significant problem with saturated animal fats is that they cause our cells to become more insulin resistant.11 As a result, insulin—a hormone that speeds up the growth of cancer—tends to stay at higher serum levels.12
Sugar and Refined Carbohydrates
Sugar and refined carbohydrates cause blood glucose levels to surge and in response, the pancreas releases large amounts of insulin. Both of these physiologic conditions accelerate the growth of breast cancer. Sugar is the principal fuel source for cancer. The more one eats of it, the faster cancer will grow. A study published in August 2004 in the journal Cancer Epidemiology, Biomarkers and Prevention found that women who ate high carbohydrate diets had twice the risk of breast cancer.14
Insulin has two major ill effects when it comes to cancer—it facilitates glucose getting into tumor cells, and promotes tumor growth. There are insulin receptors on tumor cells and when this hormone attaches to them, it causes cell division to speed up. Given these facts, it is easy to understand why women with consistently elevated serum levels of insulin are at much greater risk for being diagnosed with breast cancer. A 1998 study found that women with the highest insulin levels were 283% more likely to get breast cancer.15
Alcohol
Research shows that we need to seriously rethink the recommendation to consume a glass of alcohol a day for good health. Alcohol, particularly red wine, may decrease the risk of cardiovascular disease—but—it significantly increases the risk of breast cancer. In fact, studies show that there is a direct linear relationship between alcohol consumption and breast cancer: One drink a day increases the risk by 11%;16 two drinks by 22% to 40%; and three drinks by 33 to 70%.17 Dana-Farber Cancer Institute researcher Wendy Chen, MD PhD reported at the 2005 annual meeting of the American Society of Clinical Oncology that even an average of a half of a glass of alcohol a day could increase the risk by 6% in premenopausal women and 18% in postmenopausal women.
Astounding Protection from Plants
The medical literature is filled with studies documenting that the most health-promoting diet you can consume is plant-based. Plants are nutrient-dense. Not only are they packed full of the vitamins, minerals and other nutrients essential for your health, but they also contain hundreds of plant-chemicals known as “phyto-chemicals” that act like natural medicines. If you eat a wide variety of plants—in particular fresh, organically-grown plants including vegetables, fruits, nuts seeds, whole grains, spices and herbs—your risk of not only breast cancer, but also every other type of chronic disease is dramatically reduced.
Superfoods for Super Protection
There are a variety of foods with exceptional cancer-fighting properties that you will want to include in your diet every day. Because it is difficult to get the full therapeutic amounts of these foods every day, taking them as a nutritional supplement may be the best approach.
Two great examples are green tea and the Indian spice turmeric. Both green tea and turmeric contain extraordinary anticancer properties and have been extensively researched. Our understanding of their mechanisms of action against breast cancer is extremely sophisticated. Green tea is highly protective in general against many different types of cancers and chronic degenerative disorders due to its potent antioxidant36 and anti-inflammatory properties.37 Women who regularly drink green tea have a much lower incidence of breast cancer.38, 39 Tea drinkers diagnosed with breast cancer have a significantly better prognosis.40 Researchers have discovered many specific reasons for these statistics. For instance, green tea decreases the body’s production of estradiol (the strongest and most abundant form of natural estrogen produced by the body and the type most associated with an increased risk of breast cancer) andincreases the number of serum sex hormone-binding globulin proteins41which results in lower serum free estrogen (freeestrogen can attach to estrogen receptors in breast cells but protein-bound estrogen cannot).
Green tea is also very beneficial for those with breast cancer because it reduces the risk of metastasis42 and recurrences,43 inhibits vascular endothelial growth factor (VEGF) 44, 45 thus blocks tumor angiogenesis or new blood vessel growth into the tumors, 46, 47 and enhances the effectiveness of chemotherapy through a pump-mechanism in the cell membrane that causes chemotherapy to concentrate 2 to 3 times greater than normal in tumor cells. It also protects against the damaging effects of these drugs by pumping chemotherapy out of normal cells.48, 49
Turmeric—responsible for the bright yellow-orange color in curry—has so many health-promoting and -protecting qualities, it is considered one of—if not the—most spectacularly medicinal spices ever researched. It is the most researched plant in the medical literature with over 15,000 published studies that reveal its impressive broad health-enhancing properties, as well as the very specific ways it guards against various diseases. For instance, turmeric displays powerful anti-inflammatory50, antioxidant (about 300 times greater than vitamin E) 51 and immune boosting effects52, and it also has very specific anticancer actions, especially against breast cancer. Some of those precise actions include inhibiting phase 1 and enhances phase 2 enzymes in the liver,53,54reducing the formation of carcinogens,55 causing tumor cell death,56 slowing tumor cell division and growth,57 blocking IL-6 (a substance in the immune system that causes cancer cells to grow faster),58 inhibiting tumor invasion59 and metastasis,60 slowing down tumor angiogenesis by suppressing vascular endothelial growth factor (VEGF),61 decreasing the estrogenic effect of organo-chlorine pesticides,62,63 blocking the estrogen receptor,64,65 and down-regulating the estrogen receptor.66 Turmeric also improves the effectiveness of standard Western medical treatments. Not only does it work synergistically with radiation to enhance tumor cell death,67 but just like green tea, it also enhances the effectiveness of chemotherapy while protecting against the organ damage it can cause.68 Interestingly, turmeric also has synergistic effects with green tea. It enhances green tea’s anticancer effects by 8 times and green tea enhances turmeric’s anticancer effects by 3 times69
The Profound Impact of Simple Lifestyle Choices
In addition to foods and supplements, certain lifestyle choices also have enormous influence on the risk of breast cancer. For example, the number of hours and the timing of the hours that one sleeps impacts the risk of breast cancer by 50% or more. Going to bed by 10 PM and getting up by 6 AM enhances normal diurnal hormonal fluctuations—particularly of melatonin. Best known for its sleep-enhancing effects, melatonin also has many potent health-protecting properties including against breast cancer. In particular, it is a powerful antioxidant, and decreases the production of estrogen70, as well as several other breast-cancer growth factors.71 Working the night shift causes the greatest disturbance in melatonin and the health consequences can be quite alarming. Studies show that women who work all night and sleep during the day have the lowest levels of melatonin and a 50% higher incidence of breast cancer. 72
Daily exercise is another lifestyle choice that can dramatically cut the risk of breast cancer. Research shows that those who exercise aerobically three to five times a week for at least 30 minutes a day can reduce their risk by 20% to 50%.73,74According to a study published May 25, 2005 in Journal of the American Medical Association,75 even a brisk 30 minute walk a day can significantly reduce the risk of dying in women with breast cancer.
Chronic stress has extremely damaging effects on your body and according to the National Institute of Health, contributes to over 90% of all illnesses—mental and physical. Ancient systems of medicine including Traditional Chinese Medicine and Ayurveda, understood this and developed several effective stress-reducing techniques which train your nervous system to be less reactive to stress. Research shows these techniques, especially a form of meditation called Transcendental Meditation, are so effective at reducing the damaging effects of stress, if practiced daily, they can cut your risk of chronic disease in half.
Largely Preventable
It’s an old cliché but profound with truth: an ounce of prevention is worth a pound of cure. Research dollars for breast cancer go primarily to the investigation of new drugs and treatments. But the breast cancer epidemic will never be stopped if our focus stays on trying to fight it after the fact. It will only end with preventive measures. Research shows that breast cancer is a largely preventable disease. Yes, there will always be those women who do everything right and still get the disease. But studies indicate that the incidence of this epidemic disease could potentially be reduced in the US (currently 141:100,000 in Caucasians) to at least that found in rural China or India where it is only 8:100,000. The key is favoring the foods and lifestyle choices that protect against the disease and avoiding those that fuel it. Through educating ourselves and our patients about the many research-proven natural approaches that protect against and fight breast cancer, breast cancer could become a rare disease.
Summary of What to Favor and What to Avoid
Avoid
- Red Meat
- Saturated animal fats
- Sugar and refined carbohydrates
- Processed and packaged foods
- Alcohol
- Excess stress
- Staying up too late at night (past 10 PM)
- Sedentary lifestyle
- Being overweight or obese
- Smoking
- Exposure to toxins (building supplies, household cleaners, personal care products, and EMFs from electrical and wireless devices)
- Spending time with toxic people
Favor
- Plant-based diet: include a wide variety of organically grown fruits, vegetables, nuts, seed whole grains, spices and herbs.
- Superfoods: flax seeds, green tea, turmeric, garlic
- Nutritional Supplements: Vitamin D3, Protective Breast Formula (a combination of 7 different powerful breast-health nutrients), Brevail (flax seed lignans), omega-3 fatty acids
- Sleeping between 10 PM and 6 AM
- Keeping your weight ideal
- Daily exercise: at least 30 minutes of brisk walking a day
- Daily practice of an effective stress-reducing technique such as meditation, yoga, tai chi, Qi gong
- Spending time with loving and supportive friends
- Practicing gratitude
Christine Horner, MD is a board certified and nationally recognized surgeon, author, expert in natural medicine, and a relentless champion for women's health. She spearheaded legislation in the 1990s that made it mandatory that insurance companies pay for breast reconstruction following mastectomy. She is the author of “Waking the Warrior Goddess: Dr Christine Horner’s Program to Protect Against and Fight Breast Cancer”, winner of the Independent Book Publishers Award 2006 for “Best Book in Health, Medicine, and Nutrition.” and the author of the recently released “Radiant Health Ageless Beauty: Dr. Horner’s 30-Day Program to Extraordinary Health and Longevity.” For more information go to www.drchristinehorner.com
References
- Surveillance and Risk Assessment Division, CCDP, Health Canada
- Dai,Q., et al. Cancer Epidemiol Biomarkers Prev. 2002 Sep;11(9):801-8
- Zheng, W., et al. Cancer Epidemiol Biomarkers Prev. 1999 Mar;8(3):233-9
- Cho, E., et al. J Natl Cancer Inst. 2003 Jul 16;95(14):1079-85
- Walker, P., Public Health Nutr. 2005 Jun;8(4):348-56
- Tieyu, W., et al. Environ Int. 2005 Jun 24; [Epub ahead of print]
- Battu, R.S., et al. Ecotoxicol Environ Saf. 2004 Nov;59(3):324-31
- Ben-Michael, E., et al. J Environ Pathol Toxicol Oncol. 1999;18(4):297-303
- Hankinson, S., et al. Lancet 1998 May 9;351(9113): 1393-1396
- Chan, J., et al. SCIENCE 1998. Jan 23;279: 563-566
- Marco, M., et al. Diabetes Obes Metab. 2004 Nov;6(6):402-13
- Thompson, A.D. 3rd, Kaker, S.S. FEBS Lett. 2005 Jun 6;579(14):3195-3200
- Cho, E., et al. J Natl Cancer Inst. 2003 Jul 16;95(14):1079-85
- Romieu, I., et al. Cancer Epidemiol Biomarkers Prev. 2004 Aug;13(8):1283-9
- Del Giudice, M.E., et al. Breast Cancer Res Treat. 1998 Jan;47(2):111-20
- Longnecker, M.P. Cancer Causes and Control 1994 Jan;5(1):73-82
- Rohan, T.E., et al. Cancer Causes and Control 2000 Mar;11(3):239-47
- Dos Santos Silva, I., et al. Int J cancer 2002 May 10;99(2):238-44
- LaVecchia, C., et al. Eur J Nutr. 2001 Dec;40(6):261-7
- Iqbal, M., et al Pharmacol Toxicol. 2003 Jan;92(1):33-8
- ---Treatment Update. 2000 Jan;11(10):7
- Verma, S.P., et al. Biochem Biophys Res Commun. 1997 Apr 28;233(3):692-6
- Choudhuri, T., et al. J Biol Chem. 2005 Feb 28
- Bhatnagar, R., et al. Biochem Pharmacol. 1991 May 15;41(10):1471-7
- Shao, Z.M., et al. Int J Cancer 2002 Mar 10;98(2):234-40
- Nakagawa, H., et al. Carcinogenesis. 2001 Jun;22(6):891-7
- Harris, R.M., et al. J Clin Endocrinol Metab. 2004 Apr;89(4):1779-87
- Carbanes, A., et al. Carcinogenesis. 2004 May;25(5):741-8
- Fujiki, H. Chem Rec. 2005;5(3):119-32
- Yuan, J.M., et al. Carcinogenesis 2005 Mar 31; [Epub ahead of print]
- Wu, A.H., et al. Int J Cancer. 2003 Sept 10; 106(4):574-9
- Kodama, N., et al. Oncol Rep. 2005 Mar;13(3):497-502
- Nanba, H. Ann N Y Acad Sci. 1995 Sep 30;768:243
- Kodama, N., et al. Alten Med Rev 2002 Jun;7(3):236-9
- Funahashi, H., et al. Jpn J Cancer Res. 2001 May;92(5):483-7
- Pillai, S.P., et al. J Environ Pathol Toxicol Oncol 1999; 18(3):147-58
- Hussain, T., et al. Int J Cancer. 2005 Feb 10; 113(4):660-9
- Yuan, J.M., et al. Carcinogenesis 2005 Mar 31; [Epub ahead of print]
- Wu, A.H., et al. Int J Cancer. 2003 Sept 10; 106(4):574-9
- Nakachi, K., et al. Jpn J Cancer Res. 1998 Mar;89(3):254-61
- Nagata, C., et al. Nutr Cancer. 1998;30(1):21-4
- Fujiki, H., et al. Proc Soc Exp Biol Med. 1999 Apr;220(4):225-8
- Nakachi, K. et al. Jpn J Cancer Res. 1998 Mar;89(3):254-61
- Satippour, M.R., et al. J Nutr. 2002 Aug;132(8):2307-11
- Tang, F.Y., et al. Int J Cancer. 2003 Oct 10;106(6):871-8
- Basini, G., et al. Biofactors. 2005;23(1):25-33
- Oak, M.H., et al. J Nutr Biochem. 2005 Jan; 16(1):1-8
- Sugiyama, T., Sadzuka Y. Biochim Biophys Acta 2003 Dec 5;1653(2):47-59
- Sugiyama, T., et al. Toxicology Lett. 2001 Apr 30;121(2):89-96
- Dutta, S., et al. Bioorg Med Chem Lett. 2005 May 3
- Betancor-Fernandez, A., et al. J Pharm Pharmacol. 2003 Jul;55(7):981-6
- ---Treatment Update. 2000 Jan;11(10):7
- Iqbal, M., et al Pharmacol Toxicol. 2003 Jan;92(1):33-8
- Dinkova-Kostova, A.T., et al. Mini Rev Med Chem. 2002 Dec;2(6):595-610
- Singletary, K., MacDonald, C. Cancer Lett. 2000 Jul 3; 155(1):47-54
- Choudhuri, T., et al. J Biol Chem. 2005 Feb 28
- Bhatnagar, R., et al. Biochem Pharmacol. 1991 May 15;41(10):1471-7
- Bharti, A.C., et al. J Immunol. 2003 Oct 1;171(7):3863-71
- Hahm, E.R., et al. Biochem Biophys Res Commun. 2004 Aug 20;321(2):337-44
- Choi, M.A., et al. Biochem Biophys Res Commun. 2005 Jan 7;326(1):210-7
- Shao, Z.M., et al. Int J Cancer 2002 Mar 10;98(2):234-40
- Verma, S.P., et al. Environ Health Perspectiv 1998 Dec;106(12):807-12
- Jaga, K., Duvvi, H. J R Soc Health. 2001 Jun;121(2):107-13
- Verma, S.P., et al. Biochem Biophys Res Commun. 1997 Apr 28;233(3):692-6
- Shao, Z.M., et al. Int J Cancer. 2002 Mar 10;98(2):234-40
- Goel, A., et al. Cancer Lett. 2001 Oct 30;172(2):111-8
- Baatout, S., et al. Int J Oncol. 2004 Feb;24(2):321-9
- Odot, J., et al. Int J Cancer. 2004 Sep 1;111(3):381-7
69. Khafif, A., et al. Carcinogenesis. 1998 Mar;19(3):419-24
- Sanchez-Barcelo, E.J. J Pineal Res. 2005 May;38(4):217-22
- Lemus-Wilson, A., et al. Br J Cancer 1995 Dec;72(6):1435-40
- Davis, S., et al. J Natl Cancer Inst 2001 Oct 17;93(20):1557-62
- Veerloop, J., et al. J Natl Cancer Inst 2000 Jan 19;(92) 128-135
- Moradi, T., et al. Cancer Causes Control 2000 Jul; (11): 523-531
- Holmes, M.D., JAMA 2005 May; 293(20): 2479-2486